Layers of Experiments with Adaptive Combined Design

In the field of nanofabrication, engineers often face unique challenges in resource‐limited experimental budgets, the sensitive nature of process behavior with respect to controllable variables, and highly demanding tolerance requirements. To effectively overcome these challenges, this article proposes a methodology for a sequential design of experiments through batches of experimental runs, aptly named Layers of Experiments with Adaptive Combined Design (LoE/ACD). In higher layers, where process behavior is less understood, experimental regions cover more design space and data points are more spread out. In lower layers, experimental regions are more focused to improve understanding of process sensitivities in a local, data‐rich environment. The experimental design is a combination of a space‐filling and an optimal design with a tuning parameter that is dependent on the amount of information accumulated over the various layers. The proposed LoE/ACD method is applied to optimize a carbon dioxide (epet‐CO2) assisted deposition process for fabricating silver nanoparticles with pressure and temperature variables. © 2015 Wiley Periodicals, Inc. Naval Research Logistics 62: 127–142, 2015     

An adaptive forecasting algorithm and inventory policy for products with short life cycles

Products with short life cycles are becoming increasingly common in many industries, such as the personal computer (PC) and mobile phone industries. Traditional forecasting methods and inventory policies can be inappropriate for forecasting demand and managing inventory for a product with a short life cycle because they usually do not take into account the characteristics of the product life cycle. This can result in inaccurate forecasts, high inventory cost, and low service levels. Besides, many forecasting methods require a significant demand history, which is available only after the product has been sold for some time. In this paper, we present an adaptive forecasting algorithm with two characteristics. First, it uses structural knowledge on the product life cycle to model the demand. Second, it combines knowledge on the demand that is available prior to the launch of the product with actual demand data that become available after the introduction of the product to generate and update demand forecasts. Based on the forecasting algorithm, we develop an optimal inventory policy. Since the optimal inventory policy is computationally expensive, we propose three heuristics and show in a numerical study that one of the heuristics generates near‐optimal solutions. The evaluation of our approach is based on demand data from a leading PC manufacturer in the United States, where the forecasting algorithm has been implemented. © 2004 Wiley Periodicals, Inc. Naval Research Logistics, 2004.     

The effects of model parameter deviations on the variance of a linearly filtered time series

We consider a general linear filtering operation on an autoregressive moving average (ARMA) time series. The variance of the filter output, which is an important quantity in many applications, is not known with certainty because it depends on the true ARMA parameters. We derive an expression for the sensitivity (i.e., the partial derivative) of the output variance with respect to deviations in the model parameters. The results provide insight into the robustness of many common statistical methods that are based on linear filtering and also yield approximate confidence intervals for the output variance. We discuss applications to time series forecasting, statistical process control, and automatic feedback control of industrial processes. © 2010 Wiley Periodicals, Inc. Naval Research Logistics, 2010     

Clinical Characterization of Insomnia among Veterans with PTSD: Identifying Risk Factors for Diagnosis and Treatment with Sedative-Hypnotics

Abstract

Insomnia is prevalent among Veterans with post-traumatic stress disorder (PTSD), it exacerbates PTSD symptoms, and it contributes to impaired functioning and quality of life. To improve treatment outcomes, it is important to identify risk factors for insomnia and sedative-hypnotic use. Classification and regression trees and logistic regression models were used to identify variables associated with insomnia or sedative-hypnotic use. Key findings include low insomnia diagnosis rates (3.5–5.6%) and high rates of sedative-hypnotics (44.2–49.0%). Younger Veterans and those without a breathing-related sleep disorder (BRSD) were more likely to receive an insomnia diagnosis. Veterans with greater service connection and those with an alcohol/substance use disorder were more likely to be prescribed sedative-hypnotics. Interaction terms may have identified potential groups at risk of being under-diagnosed with insomnia (i.e. non-black Veterans with psychiatric co-morbidity, black Veterans without psychiatric co-morbidity) as well as groups at risk for sedative-hypnotic use (i.e. younger Veterans without BRSD). In sum, Veterans with PTSD have high rates of sedative-hypnotic use despite minimal evidence they are effective. This is counter to recommendations indicating behavioral interventions are the first-line treatment. Policy changes are needed to reduce use of sedative-hypnotics and increase access to behavioral insomnia interventions.     

Properties of an approximate hazard transform

The calculation of the exact reliability of complex systems is a difficult and tedious task. Consequently simple approximating techniques have great practical value. The hazard transform of a system is an invertible transformation of its reliability function which is convenient and useful in both applied and theoretical reliability work. A simple calculus for finding an approximate hazard transform for systems formed by series and parallel combinations of components is extended so that it can be used for any coherent system. The extended calculus is shown to lead to conservative approximations. A first order version of the extended calculus is also discussed. This method of approximation is even more simple to use, but is not always conservative. Examples of its application indicate that it is capable of giving quite accurate results.     

An explicit general solution in linear fractional programming

A complete analysis and explicit solution is presented for the problem of linear fractional programming with interval programming constraints whose matrix is of full row rank. The analysis proceeds by simple transformation to canonical form, exploitation of the Farkas-Minkowki lemma and the duality relationships which emerge from the Charnes-Cooper linear programming equivalent for general linear fractional programming. The formulations as well as the proofs and the transformations provided by our general linear fractional programming theory are here employed to provide a substantial simplification for this class of cases. The augmentation developing the explicit solution is presented, for clarity, in an algorithmic format.     

System comparison procedures for automatic target recognition systems

Estimating the performance of an automatic target recognition (ATR) system in terms of its probability of successfully identifying a target involves extensive image collection and processing, which can be very time‐consuming and expensive. Therefore, we investigate the Wald sequential test for the difference in two proportions as a sample size‐reducing alternative to ranking and selection procedures and confidence intervals. An analysis of the test parameters leads to a practical methodology for implementing the Wald test for fairly comparing two systems, based on specific experimental goals. The test is also extended with the modified, sequentially rejective Bonferroni procedure for the multiple pairwise comparison of more than two systems. Two sampling schemes for different experimental goals are also discussed. The test methodology is applied to actual data to compare different configurations of a specific ATR system, with the results demonstrating that the modified Wald sequential procedure is a useful alternative to comparing proportions with confidence intervals, particularly when data are expensive. © 1999 John Wiley & Sons, Inc. Naval Research Logistics 46: 357–371, 1999     

The Hungarian method for the assignment problem

This paper has been presented with the Best Paper Award. It will appear in print in Volume 52, No. 1, February 2005.