均匀设计在柴油无灰节能降污添加剂配方研制中的应用

基于低压氧弹燃烧法研究了充氧压力分别为0．6MPa和0．9MPa时两种无灰型柴油添加剂不同配比对助燃性能的影响。采用均匀实验设计和Matlab回归优化的方法，得到复配体系的最优配方，并对其进行了验证。结果表明，由Matlab回归分析得到的完全二次回归模型最理想，0．6MPa时由该模型得到的最优配方为：添加剂A和B的质量分数分别是0．300‰和0．700‰，并通过实验验证得到的发热量达到最大，变化率为8．697％。0．9MPa时，结合直观分析和回归分析，得到与实际相符的最优配方：添加剂A和B的质量分数分别是0．600‰和0．900‰，此时发热量皮化率为4．453％。     

一种面向Agent的概念化建模方法*

面向Agent的建模方法为基于Agent系统的概念化描述提供了一种新的技术.针对多Agent系统分析与建模问题,扩展并规范了面向Agent概念化建模过程,定义了Agent模型及其扩展模型,并给出了形式化描述.同时,给出面向Agent的分析和设计过程,为其具体建模提供了一种高层指导.最后,与其它现有面向Agent的方法在应用方面进行了类比分析,为该方法的广泛和深入地应用研究打下基础.     

公共场所人员安全疏散评价方法探讨

公共场所安全疏散评价对于确保火灾中人员的生命安全具有重要意义。基于“性能化”防火设计的思想，对影响公共场所安全疏散的因素进行了分析，并对安全疏散的必要性能和评价程序进行了较为全面的探讨，其中包括烟气的评价、人员疏散能力的评价、疏散路线合理性的评价、疏散对策的评价等，目的在于通过合理的评价方法得出合理的疏散性能，为减少公共场所火灾造成的人员伤亡和财产损失提供帮助。     

关于奥运临时用房消防设计问题的技术探讨

由于奥运临时用房项目建设的临时性、特殊性、紧迫性，导致了部分项目的消防设计存在难以满足现行规范的问题。笔者作为消防设计审核人员，以“为建筑内人员提供安全保障；为消防人员提供消防条件，保障其生命安全；尽量减少财产损失；保护结构安全；尽量减少对正常营运的干扰。”为安全目标，利用消防性能化设计，完善了消防设计中的火灾防控技术措施。     

基于学科间差异信息的协同优化改进算法

分析了MDO(Multidisciplinary Design Optimization)中广泛应用的协同优化算法的特点和存在的问题,提出了一种基于学科间差异信息的协同优化改进算法COMI(Collaborative Optimization based on Multidisciplinary Inconsistency).利用学科间差异信息构造了系统级松弛约束和系统级罚函数,利用遗传算法作为系统级优化算法,并采用标准算例比较了标准CO(Collaborative Optimization)算法、松弛CO算法与COMI算法的性能.结果表明COMI算法在设计结果可行性和最优值上平衡性较好.     

Equity in genetic newborn screening

State‐level newborn screening allows for early treatment of genetic disorders, which can substantially improve health outcomes for newborns. As the cost of genetic testing decreases, it is becoming an essential part of newborn screening. A genetic disorder can be caused by many mutation variants; therefore, an important decision is to determine which variants to search for (ie, the panel design), under a testing budget. The frequency of variants that cause a disorder and the incidence of the disorder vary by racial/ethnic group. Consequently, it is important to consider equity issues in panel design, so as to reduce disparities among different groups. We study the panel design problem using cystic fibrosis (CF) as a model disorder, considering the trade‐offs between equity and accuracy, under a limited budget. Most states use a genetic test in their CF screening protocol, but panel designs vary, and, due to cost, no state's panel includes all CF‐causing variants. We develop models that design equitable genetic testing panels, and compare them with panels that maximize sensitivity in the general population. Our case study, based on realistic CF data, highlights the value of equitable panels and provides important insight for newborn screening practices.     

A facility reliability problem: Formulation,properties, and algorithm

Having a robustly designed supply chain network is one of the most effective ways to hedge against network disruptions because contingency plans in the event of a disruption are often significantly limited. In this article, we study the facility reliability problem: how to design a reliable supply chain network in the presence of random facility disruptions with the option of hardening selected facilities. We consider a facility location problem incorporating two types of facilities, one that is unreliable and another that is reliable (which is not subject to disruption, but is more expensive). We formulate this as a mixed integer programming model and develop a Lagrangian Relaxation‐based solution algorithm. We derive structural properties of the problem and show that for some values of the disruption probability, the problem reduces to the classical uncapacitated fixed charge location problem. In addition, we show that the proposed solution algorithm is not only capable of solving large‐scale problems, but is also computationally effective. © 2009 Wiley Periodicals, Inc. Naval Research Logistics, 2010     

概念层次网络中对偶性设计

首先对概念层次网络（ＨＮＣ）理论作简要说明，然后根据ＨＮＣ中层符号个性化设计理论给出对偶性设计方案，和偶性的具体表现，并给出对偶性概念具体表现的注解。     

程控滤波器制作与探讨

系统以FPGA器件和微处理器为核心构成,由程控放大器、参数可调滤波器、简易幅频特性测试仪和控制显示单元四部分组成。其中程控放大器增益为(0~60)dB,10 dB步进;在单片FPGA器件中集成了低通、高通和椭圆三种数字滤波器;滤波器截止频率和放大器放大倍数可通过4×4键盘设置并在液晶上显示;幅频特性测试仪可绘出所测系统的幅频特性曲线。整个系统设计方案先进,精度高,各项指标均满足设计要求。     

高层建筑消防安全疏散设计

频繁发生的高层建筑火灾不仅造成了大量的财产损失和人员伤亡,而且还造成了不良的社会影响。在分析高层建筑火灾特性的基础上,结合人员在火灾情况下的避难行为和影响安全疏散的因素,分析了高层建筑安全疏散的目标及方法、时间和对策,为高层建筑消防安全疏散设计提供参考。