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161.
    
This paper examines right-hand side sensitivity analysis in linear programming as a problem in optimal sampling. Specifically, the insensitivity point of a solution is defined as the point at which the expected gain from increased accuracy in the prediction of a resource level is equal to the expected cost of procuring the information. The problem is structured using the rudiments of optimal statistical decision theory.  相似文献   
162.
    
This paper discusses situations in which the distribution of a lifetime response variable T is taken to depend upon a vector x of regressor variables. We specifically consider the case in which T, given x , has an exponential distribution, and in which x represents levels of fixed factors in an experimental design. Methods of analyzing data under this type of model are discussed, with maximum likelihood and least squares methods being presented and compared.  相似文献   
163.
    
The purpose of this paper is to investigate the problem of constructing an appointment template for scheduling patients at a specific type of multidisciplinary outpatient clinic called an integrated practice unit (IPU). The focus is on developing and solving a stochastic optimization model for a back pain IPU in the face of random arrivals, an uncertain patient mix, and variable service times. The deterministic version of the problem is modeled as a mixed integer program with the objective of minimizing a weighted combination of clinic closing time (duration) and total patient waiting time (length of stay). A two‐stage stochastic program is then derived to account for the randomness and the sequential nature of the decisions. Although it was not possible to solve the two‐stage problem for even a limited number of scenarios, the wait‐and‐see (WS) problem was sufficiently tractable to provide a lower bound on the stochastic solution. The introduction of valid inequalities, limiting indices, and the use of special ordered sets helped to speed up the computations. A greedy heuristic was also developed to obtain solutions much more quickly. Out of practical considerations, it was necessary to develop appointment templates with time slots at fixed intervals, which are not available from the WS solution. The first to be derived was the expected value (EV) template that is used to find the expected value of the EV solution (EEV). This solution provides an upper bound on the objective function value of the two‐stage stochastic program. The average gap between the EEV and WS solutions was 18%. Results from extensive computational testing are presented for the EV template and for our adaptation of three other templates found in the literature. Depending on the relative importance of the two objective function metrics, the results demonstrate the trade‐off that exists between them. For the templates investigated, the “closing time” ranged from an average of 235 to 275 minutes for a 300‐minute session, while the corresponding “total patient time in clinic” ranged from 80 to 71 minutes.  相似文献   
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