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41.
This article analyzes the location-allocation problem for distribution from a single fixed origin via transshipment terminals to a continuous uniformly distributed demand. Distribution through terminals concentrates flows on the origin-to-terminal links and transportation economies of scale encourage the use of larger vehicles. Analytical expressions are derived for the optimal terminal locations, the optimal allocation of destinations to terminals, and the optimal transportation cost. Continuous analytic models assume either an allocation, by partitioning the service region into sectors, or terminal locations. This is unlikely to produce an optimal distribution system. The optimal cost is compared to the cost for suboptimal location-allocation combinations. Results indicate that the location decision is not too important if destinations are allocated optimally and that allocation to the nearest terminal may be poor, even with optimal locations. © 1992 John Wiley & Sons, Inc.  相似文献   
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Abstract

Insomnia is prevalent among Veterans with post-traumatic stress disorder (PTSD), it exacerbates PTSD symptoms, and it contributes to impaired functioning and quality of life. To improve treatment outcomes, it is important to identify risk factors for insomnia and sedative-hypnotic use. Classification and regression trees and logistic regression models were used to identify variables associated with insomnia or sedative-hypnotic use. Key findings include low insomnia diagnosis rates (3.5–5.6%) and high rates of sedative-hypnotics (44.2–49.0%). Younger Veterans and those without a breathing-related sleep disorder (BRSD) were more likely to receive an insomnia diagnosis. Veterans with greater service connection and those with an alcohol/substance use disorder were more likely to be prescribed sedative-hypnotics. Interaction terms may have identified potential groups at risk of being under-diagnosed with insomnia (i.e. non-black Veterans with psychiatric co-morbidity, black Veterans without psychiatric co-morbidity) as well as groups at risk for sedative-hypnotic use (i.e. younger Veterans without BRSD). In sum, Veterans with PTSD have high rates of sedative-hypnotic use despite minimal evidence they are effective. This is counter to recommendations indicating behavioral interventions are the first-line treatment. Policy changes are needed to reduce use of sedative-hypnotics and increase access to behavioral insomnia interventions.  相似文献   
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The problem is to protect a set of t targets by n perfect interceptors against an attack by m perfect weapons. If the defender solves for an optimal preallocated preferential defense and associated game value assuming m1 attackers, and the attacker knows the assumption of the defender and utilizes m2 attackers, he may be able to achieve significantly more damage than had the defender assumed that there would be m2 attackers. The article treats the robustness of preallocated preferential defense to assumptions about the size of the attack and presents results of an alternative approach.  相似文献   
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We develop the solution to a simple problem of target selection in Lanchester combat against two enemy force types each of which undergoes a “linear-law” attrition process. In addition to the Pontryagin maximum principle, the theory of singular extremals is required to solve this problem. Our major contribution is to show how to synthesize the optimal target selection policies from the basic optimality conditions. This solution synthesis methodology is applicable to more general dynamic (tactical) allocation problems. For constant attrition-rate coefficients we show that whether or not changes can occur in target priorities depends solely on how survivors are valued and is independent of the type of attrition process.  相似文献   
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Individual characteristics of multiple-constrained resource, project scheduling problems are examined in an attempt to predict the solution obtainable with heuristic methods. Difficulties encountered in performing this type of research are described, and several multiple regression models are developed for predicting heuristic performance. Both single and multiple project data are examined, and results reported demonstrate the efficacy of determining beforehand the method used for problem solution.  相似文献   
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The simplex method is interpreted as a labeling procedure for certain classes of multicommodity flow problems in a manner similar to that for single commodity networks. As opposed to general multicommodity algorithms, no explicit matrix inversion is required; all simplex operations are performed graph-theoretically.  相似文献   
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