Evergreening and operational risk under price competition

“Evergreening” is a strategy wherein an innovative pharmaceutical firm introduces an upgrade of its current product when the patent on this product expires. The upgrade is introduced with a new patent and is designed to counter competition from generic manufacturers that seek to imitate the firm's existing product. However, this process is fraught with uncertainty because the upgrade is subject to stringent guidelines and faces approval risk. Thus, an incumbent firm has to make an upfront production capacity investment without clarity on whether the upgrade will reach the market. This uncertainty may also affect the capacity investment of a competing manufacturer who introduces a generic version of the incumbent's existing product but whose market demand depends on the success or failure of the upgrade. We analyze a game where capacity investment occurs before uncertainty resolution and firms compete on prices thereafter. Capacity considerations that arise due to demand uncertainty introduce new factors into the evergreening decision. Equilibrium analysis reveals that the upgrade's estimated approval probability needs to exceed a threshold for the incumbent to invest in evergreening. This threshold for evergreening increases as the intensity of competition in the generic market increases. If evergreening is optimal, the incumbent's capacity investment is either decreasing or nonmonotonic with respect to low end market competition depending on whether the level of product improvement in the upgrade is low or high. If the entrant faces a capacity constraint, then the probability threshold for evergreening is higher than the case where the entrant is not capacity constrained. Finally, by incorporating the risk‐return trade‐off that the incumbent faces in terms of the level of product improvement versus the upgrade success probability, we can characterize policy for a regulator. We show that the introduction of capacity considerations may maximize market coverage and/or social surplus at incremental levels of product improvement in the upgrade. This is contrary to the prevalent view of regulators who seek to curtail evergreening involving incremental product improvement. © 2016 Wiley Periodicals, Inc. Naval Research Logistics 63: 71–89, 2016     

Northern Ireland and minimum force: the refutation of a concept?

The debate over whether there exists a British counter-insurgency tradition of minimum force is one that has been thoroughly discussed. Is there anything left to say? This study suggests there is further insight to be attained if one explicitly evaluates the concept of minimum force in relation to the conduct of the security forces in the years of the Northern Ireland conflict. Through an examination of three key periods in the conflict, it will be shown that while there was invariably an awareness of the need to act with restraint among senior officers at the strategic level, this was often difficult to apply at the tactical level in the heat of confrontation. The argument demonstrates that the British Army, and other instruments of the state, rarely acted in a manner that could be described as ‘minimal’. Instead, it was the broader liberal values of the British state that explains largely the degrees of restraint exhibited by the government and security forces.     

Conflict and fiscal capacity

We examine the role of war in retarding state fiscal capacity in developing countries, measured by tax revenue ratios to GDP. We build a simple theoretical model of a factionalized state, where patronage substitutes for common interest public goods, along with violent contestation over a rent or prize. Our dynamic panel empirical analysis applied to 79 developing countries, during 1980–2010, indicates that war, especially civil war, retards fiscal capacity, along with imperfect democracy, political repression, poor governance, and dependence on oil and macroeconomic mismanagement. High intensity conflict is particularly destructive of state capacity. In countries experiencing low intensity wars, other institutional factors may matter more than war. The diminution of fiscal capacity due to war appears less pronounced after the end of the cold war.     

Variance of the number of units produced on a transfer line with buffer inventories during a period of length T

The transfer-line models in the literature are planning models rather than operational models. That is, they are very useful for planning or designing the transfer line, but are less useful for controlling the daily operation of the line. The performance measure used in these models is the efficiency of the line A. The expected number of units produced during a period of length T cycles is AT. In this article a procedure is presented for calculating the variance of the number of units produced by the transfer line during a period of length T cycles. These two performance measures can be used to construct an interval estimate for, say, the number of units produced during a shift. This interval estimate is an operational guide for the production manager.     

Scheduling customer arrivals to a stochastic service system

An efficient algorithm for determining the optimal arrival schedule for customers in a stochastic service system is developed. All customers arrive exactly when scheduled, and service times are modeled as iid Erlang random variables. Costs are incurred at a fixed rate per unit of time each customer waits for service, and an additional cost is incurred for every unit of time the server operates beyond a scheduled closing time. The objective is to minimize total operating cost. This type of problem arises in many operational contexts including transportation, manufacturing, and appointment‐based services. © 1999 John Wiley & Sons, Inc. Naval Research Logistics 46: 549–559, 1999     

Decomposition algorithms for the maximum-weight connected graph problem

Given a positive integer R and a weight for each vertex in a graph, the maximum-weight connected graph problem (MCG) is to find a connected subgraph with R vertices that maximizes the sum of their weights. MCG has applications to communication network design and facility expansion. The constrained MCG (CMCG) is MCG with a constraint that one predetermined vertex must be included in the solution. In this paper, we introduce a class of decomposition algorithms for MCG. These algorithms decompose MCG into a number of small CMCGs by adding vertices one at a time and building a partial graph. They differ in the ordering of adding vertices. Proving that finding an ordering that gives the minimum number of CMCGs is NP-complete, we present three heuristic algorithms. Experimental results show that these heuristics are very effective in reducing computation and that different orderings can significantly affect the number of CMCGs to be solved. © 1998 John Wiley & Sons, Inc. Naval Research Logistics 45: 817–837, 1998     

Automated air load planning

We describe the development of a heuristic algorithm for determining efficient 2-dimensional packings in cargo aircraft where cargo placement constraints are critically important in determining the feasibility of packing locations. We review the performance of a new algorithm versus some traditional ones for aircraft loading. The algorithm is also tested in a more generalized setting where there exist no additional constraints on items, to suggest applicability in other environments. The new algorithm has been used worldwide in the Automated Air Load Planning System (AALPS) for cargo aircraft loading, with much success. © 1998 John Wiley & Sons, Inc. Naval Research Logistics 45: 751–768, 1998     

Markovian models of three‐on‐one combat involving a hidden defender

In this paper, Markovian models of three‐on‐one stochastic firefights between ground‐based weapon systems are developed. These models address a common scenario of interest to the military, but one which has been much neglected in analytic combat models, that of combat between a hidden defender and an exposed attacking force. Each combatant must detect an opponent before commencing their firing cycle, a task which is considerably more difficult for the attacker. In the models developed here, the defender detects the exposed attacking group after an exponentially distributed time interval, while each attacker has a fixed probability of detecting the defender via the flash signature produced after each shot fired by him. The utility of the approach is demonstrated by investigating what impact the introduction of a coordinated gun‐laying system for the attacking force might have, a system made possible by battlefield digitization. The method used here allows models to be developed incrementally. This and other advantages of the Markovian approach are discussed. © 2002 Wiley Periodicals, Inc. Naval Research Logistics 49: 627–646, 2002; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/nav.10041     

Analysis of down times of jib cranes—A stochastic approach

In this paper a case study dealing with the maintenance problem of jib cranes is presented. A jib crane is viewed as a complex system whose performance is observed as a single realization over period of time. After pointing out limitations of existing stochastic models to analyze the observed realization a new family of bivariate stochastic processes is introduced. The data of jib crane is analyzed using new model and cross‐validated using part of the data set. It is noted that the new family of stochastic processes is useful to analyze bivariate data where one of the variables is finitely valued and the other is nonnegative and continuous. © 2002 Wiley Periodicals, Inc. Naval Research Logistics 49: 231–243, 2002; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/nav.10006