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281.
本文在CADKEY绘图软件包的支持下,开发了加筋圆柱结构CAD系统—Hcadx.此系统通过菜单引导用户的操作,可用经验公式或解析法作轴压稳定分析,用罚函数法优化参数,可以在不退出Hcadx的情况下启动CADKEY,自动绘制设计草图。此草图经过适当地编辑、修改、便可成为工程中能接受的工作图纸。  相似文献   
282.
State‐level newborn screening allows for early treatment of genetic disorders, which can substantially improve health outcomes for newborns. As the cost of genetic testing decreases, it is becoming an essential part of newborn screening. A genetic disorder can be caused by many mutation variants; therefore, an important decision is to determine which variants to search for (ie, the panel design), under a testing budget. The frequency of variants that cause a disorder and the incidence of the disorder vary by racial/ethnic group. Consequently, it is important to consider equity issues in panel design, so as to reduce disparities among different groups. We study the panel design problem using cystic fibrosis (CF) as a model disorder, considering the trade‐offs between equity and accuracy, under a limited budget. Most states use a genetic test in their CF screening protocol, but panel designs vary, and, due to cost, no state's panel includes all CF‐causing variants. We develop models that design equitable genetic testing panels, and compare them with panels that maximize sensitivity in the general population. Our case study, based on realistic CF data, highlights the value of equitable panels and provides important insight for newborn screening practices.  相似文献   
283.
We study a stochastic outpatient appointment scheduling problem (SOASP) in which we need to design a schedule and an adaptive rescheduling (i.e., resequencing or declining) policy for a set of patients. Each patient has a known type and associated probability distributions of random service duration and random arrival time. Finding a provably optimal solution to this problem requires solving a multistage stochastic mixed‐integer program (MSMIP) with a schedule optimization problem solved at each stage, determining the optimal rescheduling policy over the various random service durations and arrival times. In recognition that this MSMIP is intractable, we first consider a two‐stage model (TSM) that relaxes the nonanticipativity constraints of MSMIP and so yields a lower bound. Second, we derive a set of valid inequalities to strengthen and improve the solvability of the TSM formulation. Third, we obtain an upper bound for the MSMIP by solving the TSM under the feasible (and easily implementable) appointment order (AO) policy, which requires that patients are served in the order of their scheduled appointments, independent of their actual arrival times. Fourth, we propose a Monte Carlo approach to evaluate the relative gap between the MSMIP upper and lower bounds. Finally, in a series of numerical experiments, we show that these two bounds are very close in a wide range of SOASP instances, demonstrating the near‐optimality of the AO policy. We also identify parameter settings that result in a large gap in between these two bounds. Accordingly, we propose an alternative policy based on neighbor‐swapping. We demonstrate that this alternative policy leads to a much tighter upper bound and significantly shrinks the gap.  相似文献   
284.
现存的被动式外骨骼存在助力效果不明显等缺陷。基于人体步态特征,提出了将人体行走过程中的重力势能转化为人体抬腿过程中动能的原理,通过弹簧、曲柄滑块机构、棘轮棘爪机构以及链传动机构的组合,设计了一款被动式下肢机械外骨骼,并通过外骨骼动力学分析和生理消耗指数实验测试的方法进行了外骨骼性能评价。动力学分析结果表明,穿戴外骨骼后髋关节峰力矩总量降低了23.43%,髋关节做功总量降低了30.59%,初步验证了外骨骼的有效性。生理消耗指数实验测试结果表明, 穿戴外骨骼对于短距离动作转换未产生显著效果,但在长距离行走和上坡行走中分别降低了8.1%和10.4%的能量消耗。因此,该下肢外骨骼助力性能得到了验证,为相关领域的研究提供了实例化参考。  相似文献   
285.
This paper presents an actuator used for the trajectory correction fuze, which is subject to high impact loadings during launch. A simulation method is carried out to obtain the peak-peak stress value of each component, from which the ball bearings are possible failures according to the results. Subsequently, three schemes against impact loadings, full-element deep groove ball bearing and integrated raceway, needle roller thrust bearing assembly, and gaskets are utilized for redesigning the actuator to effectively reduce the bearings' stress. However, multi-objectives optimization still needs to be conducted for the gaskets to decrease the stress value further to the yield stress. Four gasket's structure parameters and three bearings' peak-peak stress are served as the four optimization variables and three objectives, respectively. Optimized Latin hypercube design is used for generating sample points, and Kriging model selected according to estimation result can establish the relationship between the variables and objec-tives, representing the simulation which is time-consuming. Accordingly, two optimization algorithms work out the Pareto solutions, from which the best solutions are selected, and verified by the simulation to determine the gaskets optimized structure parameters. It can be concluded that the simulation and optimization method based on these components is effective and efficient.  相似文献   
286.
This work provides a method to predict the three-dimensional equivalent elastic properties of the filament-wound composites based on the multi-scale homogenization principle.In the meso-scale,a representative volume element(RVE)is defined and the bridging model is adopted to establish a theoretical predictive model for its three-dimensional equivalent elastic constants.The results obtained through this method for the previous experimental model are compared with the ones gained respec-tively by experiments and classical laminate theory to verify the reliability of this model.In addition,the effects of some winding parameters,such as winding angle,on the equivalent elastic behavior of the filament-wound composites are analyzed.The rules gained can provide a theoretical reference for the optimum design of filament-wound composites.  相似文献   
287.
本文基于ATDE创新教育理论,以程序设计类课程为教学阵地,对教育技术本科生创新思维培养做出了相关探索与实践。创新思维是高级的问题解决活动。培养学生的创新思维更多体现在对学生解决问题的策略应用方面。对此,本文通过给出的案例,从不同角度详细介绍了程序设计类课程对培养教育技术本科生创新思维的实施对策,以期对提高本专业建设做出有益的探索。  相似文献   
288.
装备保障信息分类与代码设计研究   总被引:2,自引:0,他引:2  
根据装备保障信息化建设的需要,分析了装备保障信息的特点,探讨了信息分类的要求并提出了装备保障信息分类方法;阐述了装备保障信息代码设计的要求、分类、形式.提出了代码设计方法。  相似文献   
289.
基于响应面法的悬架系统优化研究   总被引:3,自引:0,他引:3  
提出了应用响应面分析履带车辆悬架系统特性的方法。构建了悬架系统特性参数和整车行驶平顺性及可靠性之间的二阶响应面模型,并依据响应面分析结果,进行悬架系统的优化研究。优化结果表明了该方法的有效性。  相似文献   
290.
新装备不经部队试用就批量生产交付部队使用,是导致新装备质量水平低、长期不能形成保障能力的重要原因之一。开展部队试用是提高新装备的质量与可靠性水平,促进新装备尽快形成作战、保障能力的重要途径之一。分析了开展新装备部队试用工作的必要性,探讨了新型装甲装备部队试用的基本任务,并对如何开展装甲新装备部队试用工作提出了几点建议。  相似文献   
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