基于fMRI的静息状态脑功能复杂网络分析

分析静息状态下人脑中不同区域之间的功能连接模式对研究静息状态下人脑正常功能活动具有重要意义。基于复杂网络理论对脑功能网络进行建模,考察静息状态脑功能网络的结构和拓扑特性。结果显示,网络具有小世界性质和无标度特性。进一步引入一种概率混合模型分析网络社团结构,得到的10个子网络中包含视觉系统、听觉系统、运动系统、默认网络以及与执行和工作记忆相关的脑区。推测出静息状态脑功能网络是由这些相对独立又彼此关联的子网络组成,其中楔前叶和扣带回作为网络的关键节点,在信息调度和传递中占据重要地位。

A Functional Complex Network Analysis in the Resting Brain Based on fMRI

It is important to understand the functional activity of the human brain during the resting state by analyzing the functional connectivity between the regions.The resting-state brain functional network was constructed based on the complex network theory.The result of analyzing the structure and topology of network showed that the resting-state brain functional network was a sparse and scale-free small-world network.Furthermore,a probabilistic mixture models was introduced to detect the community structure,w...