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We present a stochastic optimization model for allocating and sharing a critical resource in the case of a pandemic. The demand for different entities peaks at different times, and an initial inventory for a central agency are to be allocated. The entities (states) may share the critical resource with a different state under a risk-averse condition. The model is applied to study the allocation of ventilator inventory in the COVID-19 pandemic by FEMA to different U.S. states. Findings suggest that if less than 60% of the ventilator inventory is available for non-COVID-19 patients, FEMA's stockpile of 20 000 ventilators (as of March 23, 2020) would be nearly adequate to meet the projected needs in slightly above average demand scenarios. However, when more than 75% of the available ventilator inventory must be reserved for non-COVID-19 patients, various degrees of shortfall are expected. In a severe case, where the demand is concentrated in the top-most quartile of the forecast confidence interval and states are not willing to share their stockpile of ventilators, the total shortfall over the planning horizon (until May 31, 2020) is about 232 000 ventilator days, with a peak shortfall of 17 200 ventilators on April 19, 2020. Results are also reported for a worst-case where the demand is at the upper limit of the 95% confidence interval. An important finding of this study is that a central agency (FEMA) can act as a coordinator for sharing critical resources that are in short supply over time to add efficiency in the system. Moreover, through properly managing risk-aversion of different entities (states) additional efficiency can be gained. An additional implication is that ramping up production early in the planning cycle allows to reduce shortfall significantly. An optimal timing of this production ramp-up consideration can be based on a cost-benefit analysis.  相似文献   
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We develop a heuristic procedure for partitioning graphs into clusters of nodes such that each cluster of nodes induces a connected subgraph with the objective of minimizing the differences within clusters as measured by the total differences between all pairs of nodes of a cluster. We apply our procedure to determine optimal delivery zones for community sections of a major newspaper while including a number of operational constraints. Our results demonstrate a 18–56% improvement in the total differences within the zones designed over the usual intuitive heuristics. Given the magnitude of the revenue generated by larger local newspapers through zoning, our method demonstrates how better zoning can significantly enhance the value of segmentation. © 2004 Wiley Periodicals, Inc. Naval Research Logistics, 2005.  相似文献   
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We present a branch‐and‐price technique for optimal staff scheduling with multiple rest breaks, meal break, and break windows. We devise and implement specialized branching rules suitable for solving the set covering type formulation implicitly, using column generation. Our methodology is more widely applicable and computationally superior to the alternative methods in the literature. We tested our methodology on 365 test problems involving between 1728 and 86400 shift variations, and 20 demand patterns. In a direct comparison with an alternative method, our approach yields significant improvements both in cpu time and in the number of problem instances solved to optimality. The improvements were particularly marked for problems involving larger numbers of feasible shifts. © 2000 John Wiley & Sons, Inc. Naval Research Logistics 47: 185–200, 2000  相似文献   
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