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This article reviews the origins and evolution of the Middle East weapons of mass destruction-free zone (WMDFZ) concept and the proposal for a 2012 conference on the subject, and explores new challenges and opportunities for regional arms control in the current regional environment. It suggests that new models may be necessary to revitalize regional arms control efforts. The establishment of a broad regional security forum could include, but should not be limited to, curtailing weapons of mass destruction through the zone approach. Even if the 2012 conference fails to materialize, or is limited to a one-time event, the proposal for such a conference has provided an important opportunity to rethink future options for a regional arms control and security process.  相似文献   
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