A cutting plane algorithm for the bilinear programming problem

In this paper we discuss the properties of a Bilinear Programming problem, and develop a convergent cutting plane algorithm. The cuts involve only a subset of the variables and preserve the special structure of the constraints involving the remaining variables. The cuts are deeper than other similar cuts.     

On the generation of deep disjunctive cutting planes

In this paper we address the question of deriving deep cuts for nonconvex disjunctive programs. These problems include logical constraints which restrict the variables to at least one of a finite number of constraint sets. Based on the works of Balas. Glover, and Jeroslow, we examine the set of valid inequalities or cuts which one may derive in this context, and defining reasonable criteria to measure depth of a cut we demonstrate how one may obtain the “deepest” cut. The analysis covers the case where each constraint set in the logical statement has only one constraint and is also extended for the case where each of these constraint sets may have more than one constraint.     

Computational results with a branch-and-bound algorithm for the general knapsack problem

In this paper, a branch-and-bound procedure is presented for treating the general knapsack problem. The fundamental notion of the procedure involves a variation of traditional branching strategies as well as the incorporation of penalties in order to improve bounds. Substantial computational experience has been obtained, the results of which would indicate the feasibility of the procedure for problems of large size.     

Efficient computational devices for the capacitated transportation problem

This paper presents the details for applying and specializing the work of Ellis Johnson [10] and [11] to develop a primal code for the well-known capacitated transportation problem. The code was developed directly from the work of Johnson, but is similar to codes developed by Glover, Karney, Klingman, and Napier [6] and Srinivasan and Thompson [14]. The emphasis in the presentation is the use of the graphical representation of the basis to carry out the revised simplex operations. This is a means of exploiting the special structure and sparseness of the constraint matrix to minimize computational effort and storage requirements. We also present the results of solving several large problems with the code developed.     

The bilinear programming problem

The paper deals with bilinear programming problems and develops a finite algorithm using the “piecewise strategy” for large-scale systems. It consists of systematically generating a sequence of expanding polytopes with the global optimum within each polytope being known. The procedure then stops when the final polytope contains the feasible region.     

Application of disjunctive programming to the linear complementarity problem

In this article we address the question of developing deep cuts for disjunctive programs using rectilinear distance measures. The method is applied to linear complementarity problems where the matrix M need not be copositive plus. Some modifications that are needed as a computational expediency are discussed. The computation results for matrix M of size up to 30 × 30 are discussed.     

A specially structured nonlinear integer resource allocation problem

We present an algorithm for solving a specially structured nonlinear integer resource allocation problem. This problem was motivated by a capacity planning study done at a large Health Maintenance Organization in Texas. Specifically, we focus on a class of nonlinear resource allocation problems that involve the minimization of a convex function over one general convex constraint, a set of block diagonal convex constraints, and bounds on the integer variables. The continuous variable problem is also considered. The continuous problem is solved by taking advantage of the structure of the Karush‐Kuhn‐Tucker (KKT) conditions. This method for solving the continuous problem is then incorporated in a branch and bound algorithm to solve the integer problem. Various reoptimization results, multiplier bounding results, and heuristics are used to improve the efficiency of the algorithms. We show how the algorithms can be extended to obtain a globally optimal solution to the nonconvex version of the problem. We further show that the methods can be applied to problems in production planning and financial optimization. Extensive computational testing of the algorithms is reported for a variety of applications on continuous problems with up to 1,000,000 variables and integer problems with up to 1000 variables. © 2003 Wiley Periodicals, Inc. Naval Research Logistics 50: 770–792, 2003.     

Evergreening and operational risk under price competition

“Evergreening” is a strategy wherein an innovative pharmaceutical firm introduces an upgrade of its current product when the patent on this product expires. The upgrade is introduced with a new patent and is designed to counter competition from generic manufacturers that seek to imitate the firm's existing product. However, this process is fraught with uncertainty because the upgrade is subject to stringent guidelines and faces approval risk. Thus, an incumbent firm has to make an upfront production capacity investment without clarity on whether the upgrade will reach the market. This uncertainty may also affect the capacity investment of a competing manufacturer who introduces a generic version of the incumbent's existing product but whose market demand depends on the success or failure of the upgrade. We analyze a game where capacity investment occurs before uncertainty resolution and firms compete on prices thereafter. Capacity considerations that arise due to demand uncertainty introduce new factors into the evergreening decision. Equilibrium analysis reveals that the upgrade's estimated approval probability needs to exceed a threshold for the incumbent to invest in evergreening. This threshold for evergreening increases as the intensity of competition in the generic market increases. If evergreening is optimal, the incumbent's capacity investment is either decreasing or nonmonotonic with respect to low end market competition depending on whether the level of product improvement in the upgrade is low or high. If the entrant faces a capacity constraint, then the probability threshold for evergreening is higher than the case where the entrant is not capacity constrained. Finally, by incorporating the risk‐return trade‐off that the incumbent faces in terms of the level of product improvement versus the upgrade success probability, we can characterize policy for a regulator. We show that the introduction of capacity considerations may maximize market coverage and/or social surplus at incremental levels of product improvement in the upgrade. This is contrary to the prevalent view of regulators who seek to curtail evergreening involving incremental product improvement. © 2016 Wiley Periodicals, Inc. Naval Research Logistics 63: 71–89, 2016